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Changes in extracellular space size and geometry in APP23 transgenic mice: A model of Alzheimer's disease

Diffusion parameters of the extracellular space (ECS) are changed in many brain pathologies, disturbing synaptic as well as extrasynaptic “volume” transmission, which is based on the diffusion of neuroactive substances in the ECS. Amyloid deposition, neuronal loss, and disturbed synaptic transmissio...

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Detalhes bibliográficos
Main Authors: Syková, Eva, Voříšek, Ivan, Antonova, Tatiana, Mazel, Tomáš, Meyer-Luehmann, Melanie, Jucker, Mathias, Hájek, Milan, Or, Michael, Bureš, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544312/
https://ncbi.nlm.nih.gov/pubmed/15630088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408235102
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