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Could vaccination with AIDSVAX immunogens have resulted in antibody-dependent enhancement of HIV infection in human subjects?

The immune-correlate analysis of the RV144 clinical trial revealed that human plasma IgA immune responses elicited by the RV144 vaccine correlated positively with a risk for HIV acquisition. This result once again emphasized that HIV vaccines can potentially have adverse effects leading to enhanceme...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Shmelkov, Evgeny, Nadas, Arthur, Cardozo, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443089/
https://ncbi.nlm.nih.gov/pubmed/25483466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21645515.2014.972148
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