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Indirect Detection of an Epitope-Specific Response to HIV-1 gp120 Immunization in Human Subjects

A specific response of human serum neutralizing antibodies (nAb) to a conformational epitope as a result of vaccination of human subjects with the surface envelope glycoprotein (gp120) of HIV-1 has not previously been documented. Here, we used computational analysis to assess the epitope-specific re...

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Detalhes bibliográficos
Main Authors: Shmelkov, Evgeny, Nadas, Arthur, Swetnam, James, Zolla-Pazner, Susan, Cardozo, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208624/
https://ncbi.nlm.nih.gov/pubmed/22076145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027279
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