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Computational Prediction of Neutralization Epitopes Targeted by Human Anti-V3 HIV Monoclonal Antibodies

The extreme diversity of HIV-1 strains presents a formidable challenge for HIV-1 vaccine design. Although antibodies (Abs) can neutralize HIV-1 and potentially protect against infection, antibodies that target the immunogenic viral surface protein gp120 have widely variable and poorly predictable cr...

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Detalhes bibliográficos
Main Authors: Shmelkov, Evgeny, Krachmarov, Chavdar, Grigoryan, Arsen V., Pinter, Abraham, Statnikov, Alexander, Cardozo, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934971/
https://ncbi.nlm.nih.gov/pubmed/24587168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089987
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