Endothelial Cells Promote Expansion of Long‐Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates

Successful expansion of bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs) would benefit many HSPC transplantation and gene therapy/editing applications. However, current expansion technologies have been limited by a loss of multipotency and self‐renewal properties ex vivo. We hypothes...

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Publicado en:Stem Cells Transl Med
Autores principales: Gori, Jennifer L., Butler, Jason M., Kunar, Balvir, Poulos, Michael G., Ginsberg, Michael, Nolan, Daniel J., Norgaard, Zachary K., Adair, Jennifer E., Rafii, Shahin, Kiem, Hans‐Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442761/
https://ncbi.nlm.nih.gov/pubmed/28297579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2016-0240
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