Endothelial Cells Promote Expansion of Long‐Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates

Successful expansion of bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs) would benefit many HSPC transplantation and gene therapy/editing applications. However, current expansion technologies have been limited by a loss of multipotency and self‐renewal properties ex vivo. We hypothes...

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Bibliographic Details
Published in:Stem Cells Transl Med
Main Authors: Gori, Jennifer L., Butler, Jason M., Kunar, Balvir, Poulos, Michael G., Ginsberg, Michael, Nolan, Daniel J., Norgaard, Zachary K., Adair, Jennifer E., Rafii, Shahin, Kiem, Hans‐Peter
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Translational Research Articles and Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442761/
https://ncbi.nlm.nih.gov/pubmed/28297579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2016-0240
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