Adaptive Upregulation of Clumping Factor A (ClfA) by Staphylococcus aureus in the Obese, Type 2 Diabetic Host Mediates Increased Virulence

Obesity and associated type 2 diabetes (T2D) are important risk factors for infection following orthopedic implant surgery. Staphylococcus aureus, the most common pathogen in bone infections, adapts to multiple environments to survive and evade host immune responses. Whether adaptation of S. aureus...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Farnsworth, Christopher W., Schott, Eric M., Jensen, Sarah E., Zukoski, Jacob, Benvie, Abigail M., Refaai, Majed A., Kates, Stephen L., Schwarz, Edward M., Zuscik, Michael J., Gill, Steven R., Mooney, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442639/
https://ncbi.nlm.nih.gov/pubmed/28320836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-16
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