Chloroquine inhibits Ca(2+) permeable ion channels-mediated Ca(2+) signaling in primary B lymphocytes

BACKGROUND: Chloroquine, a bitter tastant, inhibits Ca(2+) signaling, resulting in suppression of B cell activation; however, the inhibitory mechanism remains unclear. RESULTS: In this study, thapsigargin (TG), but not caffeine, induced sustained intracellular Ca(2+) increases in mouse splenic prima...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Biosci
Autors principals: Wu, Yi-Fan, Zhao, Ping, Luo, Xi, Xu, Jin-Chao, Xue, Lu, Zhou, Qi, Xiong, Mingrui, Shen, Jinhua, Peng, Yong-Bo, Yu, Meng-Fei, Chen, Weiwei, Ma, Liqun, Liu, Qing-Hua
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442594/
https://ncbi.nlm.nih.gov/pubmed/28546857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-017-0155-5
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars