Involvement of Large-Conductance Ca(2+)-Activated K(+) Channels in Chloroquine-Induced Force Alterations in Pre-Contracted Airway Smooth Muscle

The participation of large-conductance Ca(2+) activated K(+) channels (BKs) in chloroquine (chloro)-induced relaxation of precontracted airway smooth muscle (ASM) is currently undefined. In this study we found that iberiotoxin (IbTx, a selective inhibitor of BKs) and chloro both completely blocked s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wei, Ming-Yu, Xue, Lu, Tan, Li, Sai, Wen-Bo, Liu, Xiao-Cao, Jiang, Qiu-Ju, Shen, Jinhua, Peng, Yong-Bo, Zhao, Ping, Yu, Meng-Fei, Chen, Weiwei, Ma, Li-Qun, Zhai, Kui, Zou, Chunbin, Guo, Donglin, Qin, Gangjian, Zheng, Yun-Min, Wang, Yong-Xiao, Ji, Guangju, Liu, Qing-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378962/
https://ncbi.nlm.nih.gov/pubmed/25822280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121566
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