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TRPC5 Is a Ca(2+)-activated Channel Functionally Coupled to Ca(2+)-selective Ion Channels

TRPC5 forms non-selective cation channels. Here we studied the role of internal Ca(2+) in the activation of murine TRPC5 heterologously expressed in human embryonic kidney cells. Cell dialysis with various Ca(2+) concentrations (Ca(2+)(i)) revealed a dose-dependent activation of TRPC5 channels by in...

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Bibliografiske detaljer
Main Authors: Gross, Stefan Alfred, Guzmán, Gustavo Adolfo, Wissenbach, Ulrich, Philipp, Stephan Ernst, Zhu, Michael Xi, Bruns, Dieter, Cavalié, Adolfo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797210/
https://ncbi.nlm.nih.gov/pubmed/19815560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018192
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