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TRPC channels regulate Ca(2+)-signaling and short-term plasticity of fast glutamatergic synapses

Transient receptor potential (TRP) proteins form Ca(2+)-permeable, nonselective cation channels, but their role in neuronal Ca(2+) homeostasis is elusive. In the present paper, we show that TRPC channels potently regulate synaptic plasticity by changing the presynaptic Ca(2+)-homeostasis of hippocam...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Schwarz, Yvonne, Oleinikov, Katharina, Schindeldecker, Barbara, Wyatt, Amanda, Weißgerber, Petra, Flockerzi, Veit, Boehm, Ulrich, Freichel, Marc, Bruns, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773422/
https://ncbi.nlm.nih.gov/pubmed/31536487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000445
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