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The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation

Rapidity and specificity are characteristic features of proteolysis mediated by the ubiquitin-proteasome system. Therefore, the UPS is ideally suited for the remodeling of the embryonic stem cell proteome during the transition from pluripotent to differentiated states and its inverse, the generation...

詳細記述

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書誌詳細
出版年:Cell Death Differ
主要な著者: Nguyen, Duong Thi Thuy, Richter, Daniel, Michel, Geert, Mitschka, Sibylle, Kolanus, Waldemar, Cuevas, Elisa, Gregory Wulczyn, F
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442473/
https://ncbi.nlm.nih.gov/pubmed/28430184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.54
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