The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation

Rapidity and specificity are characteristic features of proteolysis mediated by the ubiquitin-proteasome system. Therefore, the UPS is ideally suited for the remodeling of the embryonic stem cell proteome during the transition from pluripotent to differentiated states and its inverse, the generation...

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Publicat a:Cell Death Differ
Autors principals: Nguyen, Duong Thi Thuy, Richter, Daniel, Michel, Geert, Mitschka, Sibylle, Kolanus, Waldemar, Cuevas, Elisa, Gregory Wulczyn, F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442473/
https://ncbi.nlm.nih.gov/pubmed/28430184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.54
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