Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

PCAF and ADA3 associate within the same macromolecular complexes to control the transcription of many genes, including some that regulate apoptosis. Here we show that PCAF and ADA3 regulate the expression of PACS1, whose protein product is a key component of the machinery that sorts proteins among t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Brasacchio, Daniella, Alsop, Amber E, Noori, Tahereh, Lufti, Mariam, Iyer, Sweta, Simpson, Kaylene J, Bird, Phillip I, Kluck, Ruth M, Johnstone, Ricky W, Trapani, Joseph A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442465/
https://ncbi.nlm.nih.gov/pubmed/28060382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.119
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