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Quantitative metaproteomics and activity-based probe enrichment reveals significant alterations in protein expression from a mouse model of inflammatory bowel disease

Tandem mass spectrometry based shotgun proteomics of distal gut microbiomes is exceedingly difficult due to the inherent complexity and taxonomic diversity of the samples. We introduce two new methodologies to improve metaproteomic studies of microbiome samples. These methods include the stable isot...

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Bibliographic Details
Published in:J Proteome Res
Main Authors: Mayers, Michael D., Moon, Clara, Stupp, Gregory S., Su, Andrew I., Wolan, Dennis W.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441882/
https://ncbi.nlm.nih.gov/pubmed/28052195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00938
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