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An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2
The non-receptor tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell migration, proliferation, and survival. Emerging evidence indicates that signaling by Pyk2 regulates hematopoietic cell response,...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441678/ https://ncbi.nlm.nih.gov/pubmed/28572720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S136150 |
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