Application of a novel in silico high throughput screen to identify selective inhibitors for protein–protein interactions

[Image: see text] Increasing numbers of target protein structures available for computational studies makes the structure-based screening paradigm more attractive for initial hit indentification. We have developed a novel in silico screening methodology incorporating Molecular Mechanics (MM)/implici...

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Bibliographic Details
Main Authors: Joce, Catherine, Stahl, Joshua A., Shridhar, Mitesh, Hutchinson, Mark R., Watkins, Linda R., Fedichev, Peter O., Yin, Hang
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930491/
https://ncbi.nlm.nih.gov/pubmed/20709548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.07.103
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