ロード中...

Structure of 6‐diazo‐5‐oxo‐norleucine‐bound human gamma‐glutamyl transpeptidase 1, a novel mechanism of inactivation

Intense efforts are underway to identify inhibitors of the enzyme gamma‐glutamyl transpeptidase 1 (GGT1) which cleaves extracellular gamma‐glutamyl compounds and contributes to the pathology of asthma, reperfusion injury and cancer. The glutamate analog, 6‐diazo‐5‐oxo‐norleucine (DON), inhibits GGT1...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Terzyan, Simon S., Cook, Paul F., Heroux, Annie, Hanigan, Marie H.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441403/
https://ncbi.nlm.nih.gov/pubmed/28378915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3172
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!