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Virus Particle Core Defects Caused by Mutations in the Human Immunodeficiency Virus Capsid N-Terminal Domain

The N-terminal domains (NTDs) of the human immunodeficiency virus type 1 (HIV-1) capsid (CA) protein have been modeled to form hexamer rings in the mature cores of virions. In vitro, hexamer ring units organize into either tubes or spheres, in a pH-dependent fashion. To probe factors which might gov...

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Detalhes bibliográficos
Main Authors: Scholz, Isabel, Arvidson, Brian, Huseby, Doug, Barklis, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544128/
https://ncbi.nlm.nih.gov/pubmed/15650173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1470-1479.2005
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