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Human Immunodeficiency Virus Type 1 N-Terminal Capsid Mutants Containing Cores with Abnormally High Levels of Capsid Protein and Virtually No Reverse Transcriptase

We previously described the phenotype associated with three alanine substitution mutations in conserved residues (Trp23, Phe40, and Asp51) in the N-terminal domain of human immunodeficiency virus type 1 capsid protein (CA). All of the mutants produce noninfectious virions that lack conical cores and...

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Bibliografiske detaljer
Main Authors: Tang, Shixing, Murakami, Tsutomu, Cheng, Naiqian, Steven, Alasdair C., Freed , Eric O., Levin, Judith G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC262599/
https://ncbi.nlm.nih.gov/pubmed/14610182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12592-12602.2003
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