Human Immunodeficiency Virus Type 1 N-Terminal Capsid Mutants That Exhibit Aberrant Core Morphology and Are Blocked in Initiation of Reverse Transcription in Infected Cells

A group of conserved hydrophobic residues faces the interior of the coiled-coil-like structure within the N-terminal domain of the human immunodeficiency virus type 1 (HIV-1) capsid protein (CA). It has been suggested that these residues are important for maintaining stable structure and functional...

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Detalhes bibliográficos
Main Authors: Tang, Shixing, Murakami, Tsutomu, Agresta, Beth E., Campbell, Stephen, Freed, Eric O., Levin, Judith G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114504/
https://ncbi.nlm.nih.gov/pubmed/11533199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9357-9366.2001
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