Cell-Free Hepatitis B Virus Capsid Assembly Dependent on the Core Protein C-Terminal Domain and Regulated by Phosphorylation

Multiple subunits of the hepatitis B virus (HBV) core protein (HBc) assemble into an icosahedral capsid that packages the viral pregenomic RNA (pgRNA). The N-terminal domain (NTD) of HBc is sufficient for capsid assembly, in the absence of pgRNA or any other viral or host factors, under conditions o...

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Bibliographic Details
Published in:J Virol
Main Authors: Ludgate, Laurie, Liu, Kuancheng, Luckenbaugh, Laurie, Streck, Nicholas, Eng, Stacey, Voitenleitner, Christian, Delaney, William E., Hu, Jianming
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886785/
https://ncbi.nlm.nih.gov/pubmed/27076641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00394-16
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