Impaired up-regulation of CD25 on CD4(+) T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure

Inflammation has been recognized increasingly as a critical pathologic component of a number of heart diseases. A mouse model of autoimmune myocarditis was developed to study the role of immune mediators in the development of cardiac dysfunction. We have found previously that IFN-γ deficiency promot...

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Detalhes bibliográficos
Main Authors: Afanasyeva, Marina, Georgakopoulos, Dimitrios, Belardi, Diego F., Bedja, Djahida, Fairweather, DeLisa, Wang, Yan, Kaya, Ziya, Gabrielson, Kathleen L., Rodriguez, E. Rene, Caturegli, Patrizio, Kass, David A., Rose, Noel R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544075/
https://ncbi.nlm.nih.gov/pubmed/15611472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408241102
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