Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease

Viral infections are able to induce autoimmune inflammation in the heart. Here, we investigated the role of virus-activated Toll-like receptor (TLR)3 and its adaptor TRIF on the development of autoimmune coxsackievirus B3 (CVB3) myocarditis in mice. Although TLR3- or TRIF-deficient mice developed si...

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Main Authors: Abston, Eric D., Coronado, Michael J., Bucek, Adriana, Bedja, Djahida, Shin, Jaewook, Kim, Joseph B., Kim, Eunyong, Gabrielson, Kathleen L., Georgakopoulos, Dimitrios, Mitzner, Wayne, Fairweather, DeLisa
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195533/
https://ncbi.nlm.nih.gov/pubmed/22013485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/129486
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