IL-33 Independently Induces Eosinophilic Pericarditis and Cardiac Dilation: ST2 Improves Cardiac Function

BACKGROUND: Interleukin (IL)-33 via its receptor ST2 protects the heart from myocardial infarct and hypertrophy in animal models, but paradoxically increases autoimmune disease. In this study we examined the effect of IL-33 or ST2 administration on autoimmune heart disease. METHODS AND RESULTS: We u...

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Detalhes bibliográficos
Main Authors: Abston, Eric D., Barin, Jobert G., Cihakova, Daniela, Bucek, Adriana, Coronado, Michael J., Brandt, Jessica E., Bedja, Djahida, Kim, Joseph B., Georgakopoulos, Dimitrios, Gabrielson, Kathleen L., Mitzner, Wayne, Fairweather, DeLisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874395/
https://ncbi.nlm.nih.gov/pubmed/22454393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.111.963769
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