Fatal eosinophilic myocarditis develops in the absence of IFNγ and IL17A

CD4(+) T cells play a central role in inflammatory heart disease, implicating a cytokine product associated with helper T cell effector function as a necessary mediator of this pathophysiology. IFNγ-deficient mice developed severe autoimmune myocarditis (EAM), in which mice are immunized with cardia...

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Hauptverfasser: Barin, Jobert G., Baldeviano, G. Christian, Talor, Monica V., Wu, Lei, Ong, SuFey, Fairweather, DeLisa, Bedja, Djahida, Stickel, Natalie R., LeGault, Jillian A., Cardamone, Ashley B., Zheng, Dongfeng, Gabrielson, Kathleen L., Rose, Noel R., Cihakova, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927983/
https://ncbi.nlm.nih.gov/pubmed/24048893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301282
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