Studies of the properties of human origin recognition complex and its Walker A motif mutants
The eukaryotic six-subunit origin recognition complex (ORC) governs the initiation site of DNA replication and formation of the prereplication complex. In this report we describe the isolation of the wild-type Homo sapiens (Hs)ORC and variants containing a Walker A motif mutation in the Orc1, Orc4,...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408690102 |
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