Site-Specific DNA Binding of the Schizosaccharomyces pombe Origin Recognition Complex Is Determined by the Orc4 Subunit

The mechanism by which origin recognition complexes (ORCs) identify replication origins was investigated using purified Orc proteins from Schizosaccharomyces pombe. Orc4p alone bound tightly and specifically to several sites within S. pombe replication origins that are genetically required for origi...

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Bibliographic Details
Main Authors: Kong, Daochun, DePamphilis, Melvin L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC99975/
https://ncbi.nlm.nih.gov/pubmed/11689699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.23.8095-8103.2001
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