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In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity

The relatively recent discovery and characterization of human broadly neutralizing antibodies (bnAbs) against influenza virus provide valuable insights into antiviral and vaccine development. However, the factors that influence the evolution of high-affinity bnAbs remain elusive. We therefore explor...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Wu, Nicholas C., Grande, Geramie, Turner, Hannah L., Ward, Andrew B., Xie, Jia, Lerner, Richard A., Wilson, Ian A.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440694/
https://ncbi.nlm.nih.gov/pubmed/28504265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15371
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