Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment

Adoptive cell transfer utilizing tumour-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against haematological malignancies, but significant clinical success has not yet been achieved in solid tumours due in part to the strong immunosuppressive tumour microenvir...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Kyun-Do, Bae, Seyeon, Capece, Tara, Nedelkovska, Hristina, de Rubio, Rafael G., Smrcka, Alan V., Jun, Chang-Duk, Jung, Woojin, Park, Byeonghak, Kim, Tae-il, Kim, Minsoo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440668/
https://ncbi.nlm.nih.gov/pubmed/28504276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15365
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