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RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production

In fission yeast, factors involved in the RNA interference (RNAi) pathway including Argonaute, Dicer, and RNA-dependent RNA polymerase are required for heterochromatin assembly at centromeric repeats and the silent mating-type region. Previously, we have shown that RNA-induced initiation of transcri...

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Autores principales: Sugiyama, Tomoyasu, Cam, Hugh, Verdel, André, Moazed, Danesh, Grewal, Shiv I. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC544066/
https://ncbi.nlm.nih.gov/pubmed/15615848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407641102
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