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siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription
Heterochromatic gene silencing at the pericentromeric DNA repeats in fission yeast requires the RNA interference (RNAi) machinery. The RNA-Induced Transcriptional Silencing (RITS) complex mediates histone H3 lysine 9 (H3K9) methylation and recruits the RNA-Dependent RNA Polymerase Complex (RDRC) to...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575423/ https://ncbi.nlm.nih.gov/pubmed/18657501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.07.003 |
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