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siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription

Heterochromatic gene silencing at the pericentromeric DNA repeats in fission yeast requires the RNA interference (RNAi) machinery. The RNA-Induced Transcriptional Silencing (RITS) complex mediates histone H3 lysine 9 (H3K9) methylation and recruits the RNA-Dependent RNA Polymerase Complex (RDRC) to...

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Sonraí Bibleagrafaíochta
Main Authors: Iida, Tetsushi, Nakayama, Jun-ichi, Moazed, Danesh
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575423/
https://ncbi.nlm.nih.gov/pubmed/18657501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.07.003
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