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RNAi-Mediated Targeting of Heterochromatin by the RITS Complex

RNA interference (RNAi) is a widespread silencing mechanism that acts at both the posttranscriptional and transcriptional levels. Here, we describe the purification of an RNAi effector complex termed RITS (RNA-induced initiation of transcriptional gene silencing) that is required for heterochromatin...

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Autores principales: Verdel, André, Jia, Songtao, Gerber, Scott, Sugiyama, Tomoyasu, Gygi, Steven, Grewal, Shiv I. S., Moazed, Danesh
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244756/
https://ncbi.nlm.nih.gov/pubmed/14704433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1093686
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