MOZ-TIF2 Inhibits Transcription by Nuclear Receptors and p53 by Impairment of CBP Function

Chromosomal rearrangements associated with acute myeloid leukemia (AML) include fusions of the genes encoding the acetyltransferase MOZ or MORF with genes encoding the nuclear receptor coactivator TIF2, p300, or CBP. Here we show that MOZ-TIF2 acts as a dominant inhibitor of the transcriptional acti...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Kindle, Karin B., Troke, Philip J. F., Collins, Hilary M., Matsuda, Sachiko, Bossi, Daniela, Bellodi, Cristian, Kalkhoven, Eric, Salomoni, Paolo, Pelicci, Pier Giuseppe, Minucci, Saverio, Heery, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Gene Expression
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC544007/
https://ncbi.nlm.nih.gov/pubmed/15657427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.988-1002.2005
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы