MOZ-TIF2 Inhibits Transcription by Nuclear Receptors and p53 by Impairment of CBP Function

Chromosomal rearrangements associated with acute myeloid leukemia (AML) include fusions of the genes encoding the acetyltransferase MOZ or MORF with genes encoding the nuclear receptor coactivator TIF2, p300, or CBP. Here we show that MOZ-TIF2 acts as a dominant inhibitor of the transcriptional acti...

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Detalhes bibliográficos
Main Authors: Kindle, Karin B., Troke, Philip J. F., Collins, Hilary M., Matsuda, Sachiko, Bossi, Daniela, Bellodi, Cristian, Kalkhoven, Eric, Salomoni, Paolo, Pelicci, Pier Giuseppe, Minucci, Saverio, Heery, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544007/
https://ncbi.nlm.nih.gov/pubmed/15657427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.988-1002.2005
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