Stable Binding of ATF6 to BiP in the Endoplasmic Reticulum Stress Response

Endoplasmic reticulum (ER) stress-induced activation of ATF6, an ER membrane-bound transcription factor, requires a dissociation step from its inhibitory regulator, BiP. It has been generally postulated that dissociation of the BiP-ATF6 complex is a result of the competitive binding of misfolded pro...

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Publicat a:Mol Cell Biol
Autors principals: Shen, Jingshi, Snapp, Erik L., Lippincott-Schwartz, Jennifer, Prywes, Ron
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2005
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC543992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15657421/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.3.921-932.2005
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