Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome

Neurogenesis impairment is considered a major determinant of the intellectual disability that characterizes Down syndrome (DS), a genetic condition caused by triplication of chromosome 21. Previous evidence obtained in the Ts65Dn mouse model of DS showed that the triplicated gene APP (amyloid precur...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neurobiol Dis
Autors principals: Stagni, Fiorenza, Raspanti, Alessandra, Giacomini, Andrea, Guidi, Sandra, Emili, Marco, Ciani, Elisabetta, Giuliani, Alessandro, Bighinati, Andrea, Calzà, Laura, Magistretti, Jacopo, Bartesaghi, Renata
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439029/
https://ncbi.nlm.nih.gov/pubmed/28359846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.03.012
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars