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Identification of Chemical Compounds That Inhibit Protein Synthesis in Pseudomonas aeruginosa

Four inhibitory compounds were identified using a poly-uridylic acid (polyU) mRNA-directed aminoacylation/translation (A/T) protein synthesis system composed of phenylalanyl-tRNA synthetases (PheRS), ribosomes, and ribosomal factors from Pseudomonas aeruginosa in an in vitro screen of a synthetic co...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Palmer, Stephanie O., Hu, Yanmei, Keniry, Megan, Bullard, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438914/
https://ncbi.nlm.nih.gov/pubmed/27872201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116679591
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