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Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa

Bacterial protein synthesis is the target for numerous natural and synthetic antibacterial agents. We have developed a poly(U) mRNA-directed aminoacylation/translation (A/T) protein synthesis system composed of phenylalanyl-tRNA synthetases (PheRS), ribosomes, and ribosomal factors from Pseudomonas...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hu, Yanmei, Keniry, Megan, Palmer, Stephanie O., Bullard, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958146/
https://ncbi.nlm.nih.gov/pubmed/27246774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00800-16
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