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Identification and Characterization of a Chemical Compound that Inhibits Methionyl-tRNA Synthetase from Pseudomonas aeruginosa

BACKGROUND: Pseudomonas aeruginosa is an opportunistic pathogen problematic in causing nosocomial infections and is highly susceptible to development of resistance to multiple antibiotics. The gene encoding methionyl-tRNA synthetase (MetRS) from P. aeruginosa was cloned and the resulting protein cha...

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Detalhes bibliográficos
Publicado no:Curr Drug Discov Technol
Main Authors: Robles, Sara, Hu, Yanmei, Resto, Tahyra, Dean, Frank, Bullard, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788008/
https://ncbi.nlm.nih.gov/pubmed/28359232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570163814666170330100238
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