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Formation and Processing of DNA Damage Substrates for the hNEIL Enzymes

Reactive oxygen species (ROS) are harnessed by the cell for signaling at the same time as being detrimental to cellular components such as DNA. The genome and transcriptome contain instructions that can alter cellular processes when oxidized. The guanine (G) heterocycle in the nucleotide pool, DNA,...

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Publicat a:Free Radic Biol Med
Autors principals: Fleming, Aaron M., Burrows, Cynthia J.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438787/
https://ncbi.nlm.nih.gov/pubmed/27880870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.11.030
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