Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma

Role of cyclin dependent kinase 9(CDK9) as a potential target in esophageal adenocarcinoma (EAC) is unknown. We investigated CDK9 protein expression in EAC and Barrett's esophagus and role of CDK9 in oncogenic processes of EAC in vitro and in murine xenografts. The CDK9 expression was significa...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Tong, Zhimin, Chatterjee, Devkumar, Deng, Defeng, Veeranki, Omkara, Mejia, Alicia, Ajani, Jaffer A, Hofstetter, Wayne, Lin, Steven, Guha, Sushovan, Kopetz, Scott, Krishnan, Sunil, Maru, Dipen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438684/
https://ncbi.nlm.nih.gov/pubmed/28404924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15645
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