Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma

Role of cyclin dependent kinase 9(CDK9) as a potential target in esophageal adenocarcinoma (EAC) is unknown. We investigated CDK9 protein expression in EAC and Barrett's esophagus and role of CDK9 in oncogenic processes of EAC in vitro and in murine xenografts. The CDK9 expression was significa...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Tong, Zhimin, Chatterjee, Devkumar, Deng, Defeng, Veeranki, Omkara, Mejia, Alicia, Ajani, Jaffer A, Hofstetter, Wayne, Lin, Steven, Guha, Sushovan, Kopetz, Scott, Krishnan, Sunil, Maru, Dipen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438684/
https://ncbi.nlm.nih.gov/pubmed/28404924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15645
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