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HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model

T lymphocytes against tumor-specific mutated neoantigens can induce tumor regression. Also, the size of the immunogenic cancer mutanome is supposed to correlate with the clinical efficacy of checkpoint inhibition. Herein, we studied the susceptibility of tumor cell lines from lymph node metastases o...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Schrörs, Barbara, Lübcke, Silke, Lennerz, Volker, Fatho, Martina, Bicker, Anne, Wölfel, Catherine, Derigs, Patrick, Hankeln, Thomas, Schadendorf, Dirk, Paschen, Annette, Wölfel, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438652/
https://ncbi.nlm.nih.gov/pubmed/28423700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16048
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