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Mcl-1 regulates reactive oxygen species via NOX4 during chemotherapy-induced senescence
Mcl-1, a Bcl-2 family member, is highly expressed in a variety of human cancers and is believed to enhance tumorigenic potential and chemotherapy resistance through the inhibition of apoptosis and senescence. We previously reported that Mcl-1′s regulation of chemotherapy-induced senescence (CIS) is...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438639/ https://ncbi.nlm.nih.gov/pubmed/28423654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15962 |
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