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Inhibition of Mcl-1 Promotes Senescence in Cancer Cells: Implications for Preventing Tumor Growth and Chemotherapy Resistance

Although senescence in oncogenesis has been widely studied, little is known regarding the role of this process in chemotherapy resistance. Thus, from the standpoint of enhancing and improving cancer therapy, a better understanding of the molecular machinery involved in chemotherapy-related senescenc...

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Detalhes bibliográficos
Main Authors: Bolesta, Elzbieta, Pfannenstiel, Lukas W., Demelash, Abeba, Lesniewski, Mathew L., Tobin, Megan, Schlanger, Simon E., Nallar, Shreeram C., Papadimitriou, John C., Kalvakolanu, Dhan V., Gastman, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347419/
https://ncbi.nlm.nih.gov/pubmed/22451485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06214-11
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