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The First Negative Allosteric Modulator for Dopamine D(2) and D(3) Receptors, SB269652 May Lead to a New Generation of Antipsychotic Drugs

D(2) and D(3) dopamine receptors belong to the largest family of cell surface proteins in eukaryotes, the G protein-coupled receptors (GPCRs). Considering their crucial physiologic functions and their relatively accessible cellular locations, GPCRs represent one of the most important classes of ther...

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Bibliografiska uppgifter
I publikationen:Mol Pharmacol
Huvudupphovsmän: Rossi, Mario, Fasciani, Irene, Marampon, Francesco, Maggio, Roberto, Scarselli, Marco
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438131/
https://ncbi.nlm.nih.gov/pubmed/28265019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.107607
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