Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

Calcium signalling plays a critical role in the pathogenesis of heart failure. Here we describe a cardiac protein named Myoscape/FAM40B/STRIP2, which directly interacts with the L-type calcium channel. Knockdown of Myoscape in cardiomyocytes decreases calcium transients associated with smaller Ca(2+...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Eden, Matthias, Meder, Benjamin, Völkers, Mirko, Poomvanicha, Montatip, Domes, Katrin, Branchereau, M., Marck, P., Will, Rainer, Bernt, Alexander, Rangrez, Ashraf, Busch, Matthias, Hrabě de Angelis, Martin, Heymes, Christophe, Rottbauer, Wolfgang, Most, Patrick, Hofmann, Franz, Frey, Norbert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438100/
https://ncbi.nlm.nih.gov/pubmed/27122098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11317
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller