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VEGF–PLCγ1 pathway controls cardiac contractility in the embryonic heart

The strength of the heart beat can accommodate in seconds to changes in blood pressure or flow. The mechanism for such homeostatic adaptation is unknown. We sought the cause of poor contractility in the heart of the embryonic zebrafish with the mutation dead beat. We find through cloning that this i...

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Detalhes bibliográficos
Main Authors: Rottbauer, Wolfgang, Just, Steffen, Wessels, Georgia, Trano, Nicole, Most, Patrick, Katus, Hugo A., Fishman, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172067/
https://ncbi.nlm.nih.gov/pubmed/15998812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1319405
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