Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart

The vertebrate heart possesses autoregulatory mechanisms enabling it first to sense and then to adapt its force of contraction to continually changing demands. The molecular components of the cardiac mechanical stretch sensor are mostly unknown but of immense medical importance, since dysfunction of...

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Detalhes bibliográficos
Main Authors: Bendig, Garnet, Grimmler, Matthias, Huttner, Inken G., Wessels, Georgia, Dahme, Tillman, Just, Steffen, Trano, Nicole, Katus, Hugo A., Fishman, Mark C., Rottbauer, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560411/
https://ncbi.nlm.nih.gov/pubmed/16921028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1448306
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