Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart

The vertebrate heart possesses autoregulatory mechanisms enabling it first to sense and then to adapt its force of contraction to continually changing demands. The molecular components of the cardiac mechanical stretch sensor are mostly unknown but of immense medical importance, since dysfunction of...

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Hlavní autoři: Bendig, Garnet, Grimmler, Matthias, Huttner, Inken G., Wessels, Georgia, Dahme, Tillman, Just, Steffen, Trano, Nicole, Katus, Hugo A., Fishman, Mark C., Rottbauer, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560411/
https://ncbi.nlm.nih.gov/pubmed/16921028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1448306
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