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Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads to heart failure. We recently showed that Integrin-linked Kinase (ILK), ß-Parvin and PINCH form the IPP-complex to grant tuned Protein Kinase...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hirth, Sofia, Bühler, Anja, Bührdel, John B., Rudeck, Steven, Dahme, Tillman, Rottbauer, Wolfgang, Just, Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782988/
https://ncbi.nlm.nih.gov/pubmed/26954676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150323
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