Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

An orchestrated interplay of adaptor and signaling proteins at mechano-sensitive sites is essential to maintain cardiac contractility and when defective leads to heart failure. We recently showed that Integrin-linked Kinase (ILK), ß-Parvin and PINCH form the IPP-complex to grant tuned Protein Kinase...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Hirth, Sofia, Bühler, Anja, Bührdel, John B., Rudeck, Steven, Dahme, Tillman, Rottbauer, Wolfgang, Just, Steffen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782988/
https://ncbi.nlm.nih.gov/pubmed/26954676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150323
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