GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine

GLYX-13 is a putative NMDA receptor modulator with glycine-site partial agonist properties that produces rapid antidepressant effects, but without the psychotomimetic side effects of ketamine. Studies were conducted to examine the molecular, cellular, and behavioral actions of GLYX-13 to further cha...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Liu, Rong-Jian, Duman, Catharine, Kato, Taro, Hare, Brendan, Lopresto, Dora, Bang, Eunyoung, Burgdorf, Jeffery, Moskal, Joseph, Taylor, Jane, Aghajanian, George, Duman, Ronald S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437877/
https://ncbi.nlm.nih.gov/pubmed/27634355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.202
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